For one second all I know, everything is made of snow
I was just informed that there will be a television adaptation of Ursula K. Le Guin's The Left Hand of Darkness (1969).
If the Gethenian characters are not cast with genderqueer actors, I will feel someone is missing the point.
If the Gethenian characters are not cast with genderqueer actors, I will feel someone is missing the point.

no subject
It's a reasonable question and I don't know. The reason I think it might be possible is a couple of recent TV casting decisions that made news for casting actors of the appropriate ethnicity and gender identity even when it took extra looking: Buck on The OA and Bobbie Draper on The Expanse. Both performances have been really well received, too, which should encourage more shows to follow suit. In general, it is slowly becoming accepted that trans characters can and should be cast with trans actors. Genderqueer actors would be an analogous rather than identical situation, but it does not feel to me as though it should be absolutely impossible, especially with a sufficient name to anchor the ensemble as Genly.