sovay: (Sydney Carton)
sovay ([personal profile] sovay) wrote2024-01-29 09:03 pm

The Devil is a patriot, a proper party man

After a weekend of worsening listlessness, brainlessness, and general malaise, I finally saw a doctor and seem not to have any of the currently circulating plagues, but was sent home with a new inhaler and instructions to medicate myself like the nineteenth century on account of my lungs sounding terrible. I would so very much like to be able to think about anything that matters to me. Have some links.

1. Courtesy of [personal profile] thisbluespirit: a substantial cache of British television plays on YouTube, as usual for however long it takes for the BBC to notice.

2. Courtesy of [personal profile] davidgillon: the ongoing investigation of HMS Erebus on the clock of climate change. I had somehow forgotten the pre-printed Admiralty equivalent of a black box recorder.

3. I had occasion last night to share Donald Swann's recording of "Lord of the Dance," from his Sydney Carter-penned EP Songs of Faith and Doubt (1964). I am never going to get over the existence of this version and I also happen to like it.

4. I am delighted that the latest bog body discovery went through the normal stage of checking out a recent homicide before settling on the Ice Age, but I really love the universal and automatic association with Seamus Heaney.

5. Ainsley Hawthorn's "The Sea, Like Glass" (2024) is a marvelous haunting of sea and selves.
ethelmay: (Default)

[personal profile] ethelmay 2024-01-30 04:04 am (UTC)(link)
medicate myself like the nineteenth century

Ominous! Is it Godfrey's Cordial or Lydia Pinkham's? More seriously, I am very sorry about your lungs and hope they are more comfortable soon.
davidgillon: A pair of crutches, hanging from coat hooks, reflected in a mirror (Default)

[personal profile] davidgillon 2024-01-30 07:25 am (UTC)(link)
If memory serves, codeine doesn't work on about 1 in 6 due to genetics, I seem to be one of them, and my sister mentioned recently she's in a similar position.
davidgillon: A pair of crutches, hanging from coat hooks, reflected in a mirror (Default)

[personal profile] davidgillon 2024-01-30 07:58 am (UTC)(link)
A quick google turned up:
"Genetic differences in the expression of the CYP2D6 enzyme results in differences in the extent to which codeine is metabolised. Patients deficient in or lacking this enzyme cannot convert codeine to morphine and therefore may not obtain adequate analgesic pain relief."
https://www.medsafe.govt.nz/profs/PUArticles/Mar2013Codeine.htm#:~:text=Genetic%20differences%20in%20the%20expression,obtain%20adequate%20analgesic%20pain%20relief.
and
"CYP2D6 is responsible for metabolizing a number of important drugs containing amine functional groups, including members of the following psychotropic classes: anticholinergics/parasympathomimetics, antidepressants and monoamine modulating drugs (for example, serotonin 5-HT3 receptor antagonists, monoamine oxidase inhibitors (MAOIs), serotonin reuptake inhibitors (SSRIs), and tricyclic antidepressants); antipsychotics (typical and atypical); opiates; and synthetic opiate derivatives. CYP2D6 also metabolizes several cardiac drugs from antiarrhythmic classes as well as beta blockers; some antifungals; and the antiestrogen tamoxifen.
...
Four potential CYP2D6 phenotypic subgroups exist. These groups are usually defined by the respective number of their functional alleles: ultrarapid (3), extensive (2), intermediate (1), and poor metabolizers (0). Most CYP2D6 polymorphisms result in an allele that lacks metabolic activity. However, the prevalence of poor metabolizer phenotypes varies by racial/ethnic group: Asians (∼1%), Caucasians (5–10%), and Africans (0–19%)"
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cyp2d6#:~:text=Most%20CYP2D6%20polymorphisms%20result%20in,%E2%80%9319%25)%20%5B58%5D.

Amazing one enzyme is involved in the metabolism of such a wide variety of drugs.
gwynnega: (Leslie Howard mswyrr)

[personal profile] gwynnega 2024-01-30 06:27 am (UTC)(link)
I hope the new inhaler does the trick.

Those BBC television plays look amazing.
nineweaving: (Default)

[personal profile] nineweaving 2024-01-30 07:08 am (UTC)(link)
What a lovely set of links!

I hope this new regiment will give you some relief.

Nine
nineweaving: (Default)

[personal profile] nineweaving 2024-01-30 07:21 am (UTC)(link)
I need the bottom third of my lungs back.

*hugs*

I wish could send you to Misselthwaite, for the air.

(Good heavens. I thought I typed "regimen.")

Nine
davidgillon: A pair of crutches, hanging from coat hooks, reflected in a mirror (Default)

[personal profile] davidgillon 2024-01-30 07:41 am (UTC)(link)
was sent home with a new inhaler and instructions to medicate myself like the nineteenth century on account of my lungs sounding terrible.

My sister had similar a couple of weeks ago when she was sent for a check-up from the asthma clinic at the local hospital by the nurse practioner at her GP's. The clinic nurse decided her thermometer was probably wrong when it reported she was running a temperature of 42C (107.6F), but thought she sounded so horrible she sent her straight to the duty doctor - who himself reported he could hear her breathing from his office while she was in the waiting room. New inhaler prescribed, plus ordered to use her maintenance one like it's going out of fashion.

This is from a bug she beat back at Christmas, the same one that hit me at New Year.
Recent conversation:
Me: asked how I was and when I said I was still coughing* said she'd heard some people are still coughing after six weeks.
Sis: My doctor says he's got people still coughing at 100 days.

This winter's bugs are just nasty, even when you haven't got them. Lots of things crossed for inhaled improvements.

* Fingers crossed I've finally got rid of it after a month
kore: (Default)

[personal profile] kore 2024-01-30 09:14 am (UTC)(link)
Stand Up Nigel Barton!!
luzula: a Luzula pilosa, or hairy wood-rush (Default)

[personal profile] luzula 2024-01-30 11:35 am (UTC)(link)
*goes to read about the Erebus*

Thanks for the link, and I am so sorry about the lungs and general malaise. : ((
selkie: (Default)

[personal profile] selkie 2024-01-30 05:24 pm (UTC)(link)
I CAN HELP
I AM HELPFUL
PROPOSE WHINING ABOUT BOOK UNTIL YOU VOLUNTARILY TAKE CODEINE
OR ATTEMPT, TRANSDIMENSIONALLY ALONG THE BOSWASH CORRIDOR, TO SLIP THE CODEINE TO ME
MUCH HELPING
thisbluespirit: (Default)

[personal profile] thisbluespirit 2024-01-30 05:49 pm (UTC)(link)
I'm so sorry about the lungs/medicalness/medication/lack of it etc etc etc. *sends careful hugs over, nicely packaged*

1. Courtesy of thisbluespirit: a substantial cache of British television plays on YouTube, as usual for however long it takes for the BBC to notice.

I should have said, I landed on it, because I was Googling my current Martin Jarvis Radio SNT effort, and there was a 1983 TV play adaptation of the same thing that took me there BUT one reason I was googling was because I could see the way it was going and I needed plot spoilers.* So I need to tell you that I'm listening to a thing where Martin Jarvis is breaking down and commiting suicide and then there's somehow time travel and I'm not sure how that is allowed when he's not David Collings. (Although apparently the time travel will fix everything, which, tbf, is far less Collings-esque. He would just die and probably also murder someone anyway.)

*(i.e. Murder or suicide? I need warning for faves murdering people in my ears, because it's a bit much.)

I am delighted that the latest bog body discovery went through the normal stage of checking out a recent homicide before settling on the Ice Age, but I really love the universal and automatic association with Seamus Heaney.

Oh, how nice of them to dig one up specially to cheer you up a bit!
thisbluespirit: (martin jarvis)

[personal profile] thisbluespirit 2024-01-30 08:24 pm (UTC)(link)
Boy, that Starfall AU got dark fast.

Heh! (All the moreso because my first reaction was: "What's a Starfall AU?" lol)

(What is actually the radio/television play in question?)

J. B. Priestley's Dangerous Corner, a 1981 SNT version. It also has the amusing bonus of his character having to complain that his problem is that he's not Martin. He's going to get saved by the radio as well, which I suppose is only right and proper.
thisbluespirit: (martin jarvis)

[personal profile] thisbluespirit 2024-01-31 08:33 pm (UTC)(link)
Btw, I just watched Charades & I'm now v amused at myself because this happened:

Me (right at the start, after one tiny interaction between the two characters): Oh, so he's having an affair with his wife's friend/sister, right? Or will be, whatever.

Spoiler: he was not (had a relationship with everybody else instead) but. End credits roll. It was Rosalind Ayres!

So I'm now amused that I managed to miss the completely obvious, but also I totally did clock the pair of them anyway. (Tbf, I have listened to her an awful lot more than I've watched her, but even so, I may need to go away and do some head!desking for a bit.)

(I'm sorry, you were the only person I could think of who might be remotely amused too! Or at least, would understand what I was talking about.)

Hope nothing is worse today. <3<3<3
thisbluespirit: (martin jarvis)

[personal profile] thisbluespirit 2024-02-01 10:02 am (UTC)(link)
I am deeply charmed that their connection comes through even when their characters aren't meant to have one.

They kind of might have had, actually, but they spent barely any time on screen together in it, because he went off to be his father in the flashback parts and she stayed in the 70s with his wife.

(I'm not sure I have ever seen as opposed to heard her unless one counts Titanic (1997), which I try not to.)

I mean, I have seen that myself, but not since 1997 when I was at uni and it was the only thing on the (one, one screen) cinema in Aberystwyth for sixty million weeks and a half and my little sister made me (her reason for coming to see me with my parents that time was totally because it was about the only place in the country that was still showing Titanic and she could see it again, and v cheaply too.)
thisbluespirit: (martin jarvis)

[personal profile] thisbluespirit 2024-02-01 10:33 am (UTC)(link)
Double the Martin Jarvis for your price, but at a reduction in Rosalind Ayres?

No - about equal, as both time periods went on the same time and while two actors were simultaneously in both, but they were only in the separate scenes.

(1970s Martin Jarvis is frequently either a) Period drama hero or b) person who looks like a perfect period drama hero but is in fact rotten to the core. If it's not a classic lit thing where you know the story already, you just lay your bets as best as you can and see how it goes. XD)

I have never tried to rewatch it. Every now and then I feel that I should, just to see what it looks like to me now that I actually watch movies, and then I don't think I have enough clementines.

It would certainly have a lot of familiar faces in it now. At the time Little Sis was deeply into Leo. She also watched Romeo + Juliet a lot, so she enjoyed her Tragic Teen Fave a lot!!
Edited 2024-02-01 10:34 (UTC)
pameladean: (Default)

[personal profile] pameladean 2024-01-30 08:45 pm (UTC)(link)
This all sounds like the exact opposite of fun. Also very ill-timed. I hope the new inhaler is useful and the nineteenth century steps up properly.

P.
a_reasonable_man: (Default)

[personal profile] a_reasonable_man 2024-01-31 01:23 pm (UTC)(link)
I send healing thoughts to your lungs! (And your weird response to drugs sounds familiar, as my brother is the same way.)